Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0003p037 | (1) | SRF2016

Disease takes its Toll on reproduction: Toll-like receptors and the bovine corpus luteum

Nicholls Annemieke , Payne Loren , Robinson Robert , Coffey Tracey , Woad Katie

Introduction: Toll-like receptors (TLRs) are critical mediators of the host defence against pathogens, but may also directly influence reproduction. TLR signalling pathways have been identified in bovine granulosa cells. However, despite key diseases, such as mastitis, being associated with reduced luteal function, TLRs have not been extensively examined in the corpus luteum (CL). TLRs have also been implicated in tissue repair and remodelling processes critical to the rapid t...